Korean J Health Promot > Volume 10(1); 2010 > Article
Korean Journal of Health Promotion 2010;10(1):10-15.
과체중 여자대학생의 혈중 지질농도 및 혈액성분과 염증지표와의 관계
정재현1
숙명여자대학교1, 홍익대학교2
Associations Between Blood Lipids, Blood Composition and Inflammatory Markers in Obese Female College Students
Abstract
Background
The purpose of this study was to determine the associations between blood lipids and blood composition with inflammatory markers in obese female college students. Methods: Sixty obese college females (mean age: 21.06±1.81 yr, percent body fat: 32.63±3.66%) participated in this study. We measured the following blood parameters using an enzymatic method: total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglyceride (TG), C-reactive protein (CRP), red blood cells (RBC), white blood cells (WBC), hemoglobin (Hb), and tumor necrosis factor-α(TNF-α). Percent body fat, fat mass, weight, height, and body mass index were analyzed using bio-electrical impedance (Biospace Co.). Pearson product-moment correlation and multiple linear regression were used to examine correlations between TNF-αand blood parameters Results: TNF-αwas significantly associated with HDL-C (r=-0.39, P<0.001) and Hb (r=-0.32, P=0.01). In the multiple linear regression analysis, HDL-C (t=-2.89), RBC (t=4.41), and Hb (t=-4.08) were significant predictors of TNF-α. HDL-C, RBC, and Hb accounted for variances in TNF-αin 41% of our obese female college subjects. Conclusions: To properly control the level of TNF-α in obese female college students, one of the effective strategy is to reduce HDL-C, RBC, and Hb. Korean J Health Promot 2010;10(1):10-15 Key Words: Obese female college students, Blood lipids, Blood composition, Inflammatory markers


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