Association between Metabolic Syndrome and Depression in Community-dwelling Adults

Korean J Health Promot Dis Prev > Volume 9(4); 2009 > Article

Korean J Health Promot Dis Prev 2009;9(4):296-305.

지역사회 성인에서 대사증후군과 우울증의 관련성

이영훈1

서남대학교 의과대학 예방의학교실¹, 화순전남대학교병원 전남지역암센터², 전남대학교 의과대학 예방의학교실³, 조선대학교 의과대학 예방의학교실⁴

Association between Metabolic Syndrome and Depression in Community-dwelling Adults

Abstract

Background
: Epidemiologic studies of the relationship between metabolic syndrome (MetS) and depression have reported conflicting results. We investigated whether MetS is associated with depression in community-dwelling older adults. Methods : Data for this population-based cross-sectional study were collected from 4,090 subjects (1,502 men; 2,588 women) aged 50-90 years who completed the Community Health Survey in Dong-gu, Gwangju metropolitan city between April 2007 and June 2008. MetS was defined according to the modified National Cholesterol Education Program Adult Treatment Panel Ⅲ criteria, and depression was assessed using the Center for Epidemiologic Studies Depression Scale (CES-D). The relationship between MetS and depression (CES-D ≥21) was assessed by logistic regression analysis. Results : The prevalence of MetS was 35.7% in men and 52.1% in women. After controlling for age, body mass index, smoking status, alcohol consumption, physical activity, level of education, marital status, and health security system, MetS was not associated with depression in both men (odds ratio, OR=1.23, 95% confidence interval, CI=0.65-2.33) and women (OR=0.99, 95% CI=0.75-1.31). Conclusions: This community-based cross-sectional study found no clear association between MetS and depression. Further community-based prospective studies are needed to help establish the effects of MetS on depression. (Korean J Health Promot Dis Prev 2009;9(4):296-305) Key words : Metabolic syndrome, Depression, Cross-sectional study