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Korean J Health Promot. 2010;10(1):10-15.
- 과체중 여자대학생의 혈중 지질농도 및 혈액성분과 염증지표와의 관계
- Associations Between Blood Lipids, Blood Composition and Inflammatory Markers in Obese Female College Students
- Abstract
- Background
The purpose of this study was to determine the associations between blood lipids and blood composition with inflammatory markers in obese female college students. Methods: Sixty obese college females (mean age: 21.06±1.81 yr, percent body fat: 32.63±3.66%) participated in this study. We measured the following blood parameters using an enzymatic method: total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglyceride (TG), C-reactive protein (CRP), red blood cells (RBC), white blood cells (WBC), hemoglobin (Hb), and tumor necrosis factor-α(TNF-α). Percent body fat, fat mass, weight, height, and body mass index were analyzed using bio-electrical impedance (Biospace Co.). Pearson product-moment correlation and multiple linear regression were used to examine correlations between TNF-αand blood parameters Results: TNF-αwas significantly associated with HDL-C (r=-0.39, P<0.001) and Hb (r=-0.32, P=0.01). In the multiple linear regression analysis, HDL-C (t=-2.89), RBC (t=4.41), and Hb (t=-4.08) were significant predictors of TNF-α. HDL-C, RBC, and Hb accounted for variances in TNF-αin 41% of our obese female college subjects. Conclusions: To properly control the level of TNF-α in obese female college students, one of the effective strategy is to reduce HDL-C, RBC, and Hb. Korean J Health Promot 2010;10(1):10-15 Key Words: Obese female college students, Blood lipids, Blood composition, Inflammatory markers
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